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What Is Oxycodone
Each red, round, biconvex, film-coated tablet, engraved "APO" on one side and "OCD" over "60" on the other, contains 60 mg of oxycodone hydrochloride. Nonmedicinal ingredients: anhydrous lactose, ethylcellulose, magnesium stearate, colloidal silicon dioxide, hydroxypropyl methylcellulose, hydroxypropyl cellulose, polyethylene glycol, and red iron oxide.
How should I use this medication?
The dose of oxycodone controlled release varies widely depending on the cause and severity of pain, individual medical history, and body weight. For people who are not taking opioid pain medications when oxycodone is started, the usual starting dose of controlled-release tablets is 10 mg or 20 mg every 12 hours. Your doctor can adjust your dose until a dose that controls your pain with tolerable side effects is reached. For people who are currently taking other opioid pain medications when oxycodone controlled release is started, the recommended starting dose will depend on the type and dose of opioid that is currently being taken. Your doctor will determine the appropriate dose for you. Oxycodone controlled release should be taken with a glass of water. It can be taken with or without food. The controlled-release tablets are for people who require continuous use of a pain killer for several days or more. It is taken every 12 hours (and is not taken "as needed"). The controlled-release tablets should be swallowed whole and should not be broken, cut, chewed, dissolved, or crushed. Taking broken, cut or chewed tablets can lead to the rapid release of oxycodone. This large amount of medication being absorbed into the body can be fatal. To avoid difficulty swallowing, take only one tablet at a time and take the controlled-release tablet with enough water so that you are able to completely swallow the tablet immediately after placing it in your mouth. Do not lick, pre-soak, or wet the tablet before you place it in your mouth. You may notice what appears to be a tablet in your stool. This is normal and occurs because the tablet does not completely dissolve after all the medication has been released in the body. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor. It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose of the controlled-release tablets, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. Store this medication at room temperature and protect it from moisture. Keep this medication in a safe place away from children or pets, and to prevent theft. Accidental use by a child or pet may result in death. If accidental use occurs, get immediate medical attention for the child or pet. Do not take this medication in front of children. Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What side effects are possible with this medication?Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time. Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Check with your doctor as soon as possible if any of the following side effects occur:
Are there any other precautions or warnings for this medication?Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Abdominal (stomach) conditions: Oxycodone and other narcotic medications may make the diagnosis of abdominal conditions more difficult or it may worsen these conditions. If you have abdominal problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Accidental Use: When oxycodone is used by anyone other than the person for whom it was prescribed, the effects of the medication may be fatal. Children are especially at risk. Keep this medication out of sight and reach of children. Alcohol and other medications that cause drowsiness: Do not consume alcohol while taking this medication, as this may lead to dangerous side effects. Other medications that cause drowsiness or slow down your breathing (e.g., antidepressants, sleeping pills, anxiety medications) should be avoided if possible as additive side effects may occur and can be dangerous. Constipation: Constipation happens frequently while taking opioid (narcotic) pain relievers on a regular basis. Your doctor will discuss the use of stimulant laxatives, stool softeners, and other measures to be used as required. Controlled-release: Controlled-release forms of this medication are designed to work over 12 hours when swallowed whole. If a tablet is broken, cut, crushed, dissolved, or chewed, the entire 12-hour dose will be absorbed rapidly into your body. This can be very dangerous, causing serious problems such as slowed breathing and overdose, which can be fatal. Dependence and withdrawal: As with other opioid medications (narcotics), this medication may become habit-forming if taken for long periods of time. Misuse of oxycodone is usually not a problem when it is used appropriately for pain relief. Physical dependence, or tolerance (a need to take regular doses to prevent physical symptoms) has been associated with narcotic analgesics such as oxycodone. Withdrawal symptoms may be experienced if the dose is significantly reduced or suddenly discontinued. Reducing the dose gradually under medical supervision can help prevent or decrease these withdrawal symptoms when this medication is no longer required for pain control. Withdrawal symptoms (e.g., body aches, diarrhea, nervousness, restlessness, runny nose, sneezing, goose bumps, shaking, shivering, nausea, stomach cramps, fast heart rate, fever, sweating) may occur if oxycodone is stopped suddenly. If you have been taking this medication for a long time and no longer require it for pain control, you should stop the medication gradually as directed by your doctor. Difficulty breathing: Oxycodone can cause serious breathing problems, particularly for people having an acute asthma attack or for those with chronic obstructive pulmonary disease (chronic bronchitis, emphysema) or other conditions that affect breathing. If you experience slowed breathing or difficulty breathing, seek immediate medical attention. If you have lung problems, or are taking other medications that can slow breathing, you are more at risk for experiencing this. If you have asthma or other breathing disorders, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Difficulty swallowing: There have been reports of choking and difficulty swallowing the controlled-release form of oxycodone. To avoid difficulty swallowing, take only one tablet at a time and take the controlled-release tablet with enough water so that you are able to completely swallow the tablet immediately after placing it in your mouth. Do not lick, pre-soak, or wet the tablet before you place it in your mouth. If you experience difficulty swallowing or pain after taking controlled-release oxycodone, contact your doctor immediately. Drowsiness/reduced alertness: Oxycodone may impair the mental or physical abilities needed for activities such as driving or operating machinery. Do not drive or perform other potentially hazardous tasks if this medication affects your ability to do these safely. Head injury: Oxycodone can cause increased pressure inside the head. If you have an acute head injury or any other condition which increases the pressure inside your head, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Kidney function: Kidney disease or reduced kidney function may cause this medication to build up in the body, causing side effects. If you have severely reduced kidney function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Liver function: Liver disease or reduced liver function may cause this medication to build up in the body, causing side effects. If you have severely reduced liver function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Medical conditions: If you have abnormal heart rhythms, reduced adrenal function (e.g., Addison's disease), low thyroid, inflammation of the pancreas, enlarged prostate, or urethral strictures, oxycodone may cause increased symptoms or your condition to become worse. Discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Stopping the medication: Do not suddenly stop taking this medication since withdrawal symptoms may occur. These symptoms may include body aches, diarrhea, nervousness, restlessness, runny nose, sneezing, goose bumps, shaking, shivering, nausea, stomach cramps, fast heart rate, fever, sweating, and confusion. Your doctor will advise you on how to safely stop taking this medication if you no longer require it for pain control. Uncontrolled Pain: If you experience pain that is not relieved by a normal dose of oxycodone, speak to your doctor. Do not increase the amount of this medication you are taking without medical advice. Pregnancy: This medication should not be used during pregnancy. Infants born to mothers who have taken oxycodone during pregnancy have been born with signs of narcotic withdrawal. If you become pregnant while taking this medication, contact your doctor immediately. Breast-feeding: It is not known if oxycodone passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding. Children: The safety and effectiveness of using this mediation have not been established for children. Accidental ingestion of this medication by children may lead to severe and even fatal consequences. Keep this medication out of the reach of children. Seniors: Seniors may be more sensitive to the effects of this medication.
What other drugs could interact with this medication?There may be an interaction between oxycodone and any of the following:
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
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